Laucirin

Protected lauric acid to maintain the balance of the gut microbiota

Gut health depends on the interaction between diet, the integrity of the mucosa and the balance of the gut flora: a stable gut microbiota aids digestion and nutrient absorption, reduces the incidence of gut diseases and promotes an effective immune response. Gram-positive bacteria, such as streptococci, staphylococci and clostridia, cause considerable damage to animal health and significant financial losses for the farmer. Streptococcus suis is transmitted by direct contact or spread indirectly via airborne droplets expelled during breathing. Healthy pigs can harbour the microorganism in their tonsils for several months, and sows can act as healthy carriers. The sow passes antibodies to the piglet via colostrum, which is why the disease is rare in suckling animals. The disease is very common in the early post-weaning period, often appearing 2–3 weeks after weaning and continuing until around 16 weeks of age. At weaning, almost 100 per cent of piglets become carriers within three weeks.

Lauricin

Streptococcus infection: economic damages

high mortality | 10-50%
high morbility | 5-20%
less average daily growth |-20/40 g/die
feed consumption reduction |-20-50%
feed conversion reduced |+20-40%
production loss days |+8-15 gg
drugs cost increased |+1-5 €/pig
increase general costs of work

Possible workers contagion

Gram

Gram⁺bacteria cellwall is (50-90%) constituted by peptidoglycans, while Gram^- have an additional polysaccharidic membrane (not present in Gram⁺) and a thin peptidoglycan membrane.

Among all medium chain saturated fatty acids, Lauric acid is the one having strongest antimicrobial activity against gram-positive bacteria and against some viruses and fungi.
Lauric acid is able to interpose with the peptidoglycan cell wall causing its own breaks: once inside the cell, Lauric acid may also interfere with the bacterial gene transduction and transcription processes.

Economic considerations

In the post-weaning phase, Lauricin has been shown to be an excellent substitute for, or to reduce the dosage and/or duration of use of, antibiotics commonly used to prevent streptococcosis. Compared with the control group (no antibiotics, no additives), Lauricin delivered a financial return 20 per cent higher than the market value of the piglets.

When utilize Lauricin

To reduce the incidence of Streptococcus-related problems
To prevent post-weaning diarrhoea
During the transition between feeds of different quality
In situations of heat stress or feed restriction
To improve general health

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